CMP Scientific
Products & Services
CMP Scientific: Advancing Analytical Science Through CE-MS Innovation
CMP Scientific is a technology-focused company dedicated to the development and commercialization of capillary electrophoresis coupled with electrospray ionization mass spectrometry (CE-MS) products and solutions. Our mission is to deliver cutting-edge analytical tools that empower researchers and scientists to achieve deeper insights with higher precision.
Our product portfolio includes a comprehensive range of CE-MS components and systems, such as:
-
Integrated CE-MS instruments designed for seamless operation and robust performance
-
EMASS-II CE-MS ion sources, enabling stable and sensitive coupling between CE and MS
-
High-efficiency separation capillaries for reliable analyte resolution
-
CE-MS electrospray emitters, optimized for nanospray stability and reproducibility
-
Reagent kits for cIEF-MS, tailored for charge variant analysis in biopharmaceutical applications
-
Peripheral devices and technical services, supporting complete CE-MS workflow integration
The core of CMP Scientific’s innovation is our globally patented EMASS-II CE-MS coupling technology, which leverages an electrokinetically pumped sheath liquid nanospray ionization system. This advanced design significantly enhances the overall performance of CE-MS by improving spray stability, detection sensitivity, and operational robustness—key factors in achieving high-quality, reproducible analytical results.
Our technology has earned international recognition from leading biopharmaceutical companies and top-tier life science research institutions, who rely on our solutions for complex applications such as protein characterization, charge variant analysis, metabolomics, and biomarker discovery.
With over a decade of specialization in CE-MS and a strong foundation of more than 200 peer-reviewed scientific publications, CMP Scientific has developed a fully integrated, all-in-one CE-MS instrument to meet the rigorous demands of modern analytical laboratories. Designed for versatility and scalability, our systems support a wide range of research and quality control workflows in both academic and industrial settings.
CMP Scientific is committed to pushing the boundaries of analytical performance. Whether you're working in biopharma, clinical research, or fundamental life sciences, our CE-MS solutions are built to accelerate your discoveries and ensure reliable, data-driven outcomes.
cIEF-MS platform
Product Name: BioSummit™ CVA CE-ESI-TOF Integrated System
Catalog No.: BIOSUMMIT (Model: BIOSUMMIT-CVA)
CMP Scientific develops and manufactures the BioSummit™ CVA, a fully integrated capillary electrophoresis-mass spectrometry (CE-MS) system. Utilizing our patented EMASS-II CE-MS coupling technology, the BioSummit™ CVA ensures unparalleled precision, stability, and sensitivity. Designed for applications such as charge variant analysis, intact mass analysis, subunit investigation, and peptide mapping, this next-generation platform delivers consistent and reliable results for all your biomolecular analysis needs. This turnkey system is available for purchase for biopharmaceutical labs.
CE-MS Services
.png)
Charge variants are common in therapeutic monoclonal antibodies (mAbs). Leveraging our advanced EMASS-II CE-MS technology, CMP Scientific has developed automated online MS analysis for antibody drug charge variants, significantly enhancing detection efficiency and accuracy. Using our proprietary online CR3520 cIEF-MS platform, we have successfully characterized charge variants in a wide range of protein therapeutics, including mAbs, bispecific antibodies, fusion proteins, and ADCs.
For more information about our CE-MS services, please contact us at tech@cmpscientific.com.
ECE-001 Capillary Electrophoresis
CMP Scientific's ECE-001 CE system is designed for the coupling with mass spectrometry. It offers separate temperature controls on the sample and buffer trays. A minimum length of 50 cm separation capillary may be used on ECE-001 CE unit for both CZE-MS and cIEF-MS analysis.
EMASS-II CE-MS Ion Source
CMP Scientific's EMASS-II CE-MS ion source has been designed with mounting stages for common ESI mass spectrometers. Both positive and negative CE-MS modes are supported by EMASS-II ion source. Numerous applications have been developed using EMASS-II CE-MS ion source, including proteomics, polysaccharide analysis, monoclonal antibody intact molecule and subunits analysis, fusion protein biotransformation, and charge variants analysis by online cIEF-MS.
CR3520 cIEF-MS Reagent Kit
CMP Scientific's CR3520 cIEF-MS reagent kit enables fully automated online charge variants analysis for recombinant protein therapeutics. Excellent resolution and assay robustness have been demonstrated over 100 repeat injections of cIEF-MS analyses.
Consumables
CMP Scientific provides a wide set of consumables, providing options for various analytical purposes. The proprietary coating and manufacturing process contributes to the desirable results for cIEF-MS and CZE-MS analysis.
MB03-CE IonSpace™ Mobile Workbench
CMP Scientific's MB03-CE IonSpace™ Height-Adjustable Mobile Workbench is a highly digitally controlled, adjustable workbench. Being placed near mass spectrometers, the dead volume between capillary electrophoresis/liquid chromatography and mass spectrometry systems could be minimized. Equipped with a digital display controller, it allows for precise and stepless adjustment of the table height. Capable of withstanding a long-term load of up to 140KG, it features flexible lifting, exceptional stability, and heavy-duty casters for quiet, smooth movement. This workstation helps reduce operational risks associated with solvent bottle replacements, saves valuable space in laboratories, and mitigates the risk of moving high-end analytical instruments.
