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Products & Services

CMP Scientifc focuses its business on capillary electrophoresis coupled with electrospray mass spectrometry (CE-MS) products and technologies. Thecompany's products include CE-MS instruments, CE-MS coupled ion sources,separation capillaries, CE-MS electrospray emitters, clEF-MS reagent kits, andperipheral equipment and services.

The company's globally patented EMASS-ll CE-MS coupling technology uses anelectrokinetically pumped sheath liquid nanospray ionization technology, greatlyenhancing the overall performance of CE-MS analysis. This coupling technologyhas been recognized by analytical experts from leading biopharmaceuticalcompanies and life science research institutes worldwide for its stability andsensitivity. With over 10 years of experience in CE-MS and more than 200 published papers, CMP Scientifc has developed an all-in-one CE-MS instrument to meet the needs of laboratories around the world.
cIEF-MS platform
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CMP Scientific develops and manufactures the BioSummit™ CVA, a fully integrated capillary electrophoresis-mass spectrometry (CE-MS) system. Utilizing our patented EMASS-II CE-MS coupling technology, the BioSummit™ CVA ensures unparalleled precision, stability, and sensitivity. Designed for applications such as charge variant analysis, intact mass analysis, subunit investigation, and peptide mapping, this next-generation platform delivers consistent and reliable results for all your biomolecular analysis needs.

ECE-001 Capillary Electrophoresis
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CMP Scientific's ECE-001 CE system is designed for the coupling with mass spectrometry. It offers separate temperature controls on the sample and buffer trays. A minimum length of 50 cm separation capillary may be used on ECE-001 CE unit for both CZE-MS and cIEF-MS analysis.

CE-MS Services
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In general, many proteins, such as therapeutic monoclonal antibodies (mAbs), have charge variants. Based on the eminent EMASS-II CE-MS technology, CMP Scientific has realized automatic online MS analysis of antibody drug charge variants, which greatly improves the efficiency and accuracy of detection. So far, we have used the online cIEF-MS to complete numerous successful cases of charge variants characterization of protein drugs, including mAbs, bispecific antibodies, fusion proteins, ADC drugs.

For more information about our CE-MS services, please visit our service website, chargevariants.com.

EMASS-II CE-MS Ion Source
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CMP Scientific's EMASS-II CE-MS ion source has been designed with mounting stages for common ESI mass spectrometers. Both positive and negative CE-MS modes are supported by EMASS-II ion source. Numerous applications have been developed using EMASS-II CE-MS ion source, including proteomics, polysaccharide analysis, monoclonal antibody intact molecule and subunits analysis, fusion protein biotransformation, and charge variants analysis by online cIEF-MS.

CR3520 cIEF-MS Reagent Kit
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CMP Scientific's CR3520 cIEF-MS reagent kit enables fully automated online charge variants analysis for recombinant protein therapeutics. Excellent resolution and assay robustness have been demonstrated over 100 repeat injections of cIEF-MS analyses.

Consumables
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CMP Scientific provides a wide set of consumables, providing options for various analytical purposes. The proprietary coating and manufacturing process contributes to the desirable results for cIEF-MS and CZE-MS analysis.

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