CMP Scientific: A Global Leader in CE-MS Technologies
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CMP Scientific is a technology-driven company specializing in capillary electrophoresis coupled with electrospray ionization mass spectrometry (CE-MS) — a cutting-edge analytical approach known for its high-resolution separation and ultra-sensitive detection capabilities. Our business is fully dedicated to advancing CE-MS instrumentation, consumables, and services, enabling researchers and laboratories to tackle complex analytical challenges with precision and confidence.
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Our comprehensive product portfolio includes:
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CE-MS instrumentation, including fully integrated systems designed for ease of use and high analytical performance
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EMASS-II ion sources for seamless CE-MS coupling, offering reliable nanospray ionization
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High-performance separation capillaries and electrospray emitters, optimized for stability and reproducibility
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CR3520 cIEF-MS reagent kits, specifically formulated for charge variant analysis of biotherapeutics
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Peripheral equipment and technical services, supporting complete CE-MS workflows from research to regulated environments
At the heart of our innovation is the globally patented EMASS-II CE-MS coupling technology, which utilizes electrokinetically pumped sheath liquid nanospray ionization to ensure unmatched performance in terms of stability, sensitivity, and reproducibility. This proprietary technology has been widely adopted and endorsed by experts at leading biopharmaceutical companies and life science research institutes around the world, reinforcing our reputation for delivering robust and reliable CE-MS solutions.
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With over a decade of focused experience in CE-MS and a strong foundation of more than 200 peer-reviewed publications, CMP Scientific has pioneered the development of an all-in-one CE-MS platform that meets the evolving needs of both academic and industrial laboratories. Our technologies are playing a vital role in key application areas such as:
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Biopharmaceutical development and characterization
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Proteomics and biomarker discovery
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Metabolomics and clinical research
By combining technical innovation with real-world applicability, CMP Scientific empowers scientists to generate high-quality data with greater efficiency, precision, and confidence — ultimately accelerating research and improving decision-making across the life sciences.
Partner with CMP Scientific to unlock the full potential of CE-MS in your laboratory.

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Latest News

June 1-5, 2025
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We are excited to announce that we will be attending the 73rd ASMS from June 1-5!
We hope to see you there!
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For more information, click here.
Latest Application Note on CR3520 cIEF-MS workflow
May 25, 2025
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We’re excited to share that our latest application note on the CR3520 cIEF-MS system—focused on identifying charge variants in mAbs and ADCs—is now published!
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To read this application note, click here.
CR3520 cIEF-MS Reagent Kit

Comprehensive Reagent Solution for Automated Charge Variant Analysis of Biotherapeutics
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CMP Scientific’s CR3520 cIEF-MS Reagent Kit is a fully integrated, high-performance reagent system designed to enable automated capillary isoelectric focusing–mass spectrometry (cIEF-MS) for in-depth characterization of charge variants in biotherapeutic products.
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Optimized for use with the EMASS-II CE-MS ion source, this reagent kit simplifies and accelerates the traditionally complex workflow of charge variant analysis, delivering high-resolution separation, MS compatibility, and consistent, reproducible results. It supports regulatory-compliant workflows by facilitating precise detection and profiling of charge-related heterogeneity in monoclonal antibodies, fusion proteins, and other biologics.
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Whether in R&D or QC environments, the CR3520 cIEF-MS Reagent Kit offers a reliable, automation-ready solution for robust charge variant analysis—enhancing throughput, reducing manual labor, and increasing confidence in biopharmaceutical quality assessments.
Last Updated May 2025
About Us
CMP Scientific Corp is advancing Capillary Electrophoresis - Mass Spectrometry (CE-MS) coupling. The outstanding performance of CMP Scientific’s EMASS-II CE-MS ion source has been validated by several leading biopharmaceutical companies, top research institutes, and leading life science instrument companies.